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IPLUSO 19635

Radiopharmacy II

Medical Imaging and Radiotherapy
  • ApresentaçãoPresentation
    The CU of Radiopharmacy II aims to reinforce and consolidate the knowledge acquired at Radiopharmacy I, namely regarding the chemistry of Technetium and Iodine, in order to integrate this knowledge into the preparation and quality control of the most common SPECT radiopharmaceuticals in current clinical practice.
  • ProgramaProgramme
    1- Production of radionuclides with interest for Nuclear Medicine 2- Radiopharmaceutical chemistry and radiolabeling methods 3- Radiopharmaceuticals localization mechanisms 4- Characteristics and clinical applications of commercially available radiopharmaceuticals 5- Legal regulations 6- Activity management on the radiopharmacy
  • ObjectivosObjectives
    Students must acquire knowledge, so they be able to identify radionuclides production methods, radiopharmaceutical chemistry and radiolabeling methods for several RF, localization mechanisms for most used RF, their characteristics and clinical applications, as well as good radiopharmacy practice guidelines and related legal documents. The student must accurately execute radiopharmacy technical procedures, namely RF preparation and QC (specific QC procedures for each RF). Student must also competently prepare adults and pediatric RF doses, using decay calculus methods and radioactivity adjustment accordingly the RF and the patient characteristics. Additionally, the student must comprehend and execute lyophilized kits fractionation, in order to adequately manage the obtained activity, trough simulation at several real scenarios.
  • BibliografiaBibliography
    Saha B. (2013). Fundamentals of Nuclear Pharmacy. 6th edition. New York: Springer-Verlag. The Radiopharmacy – a Technologist’s Guide (2008). European Association of Nuclear Medicine. Guidelines on current good Radiopharmacy Practice (cGRPP) in the Preparation of Radiopharmaceuticals. (2007). European Association of Nuclear Medicine. Zolle L. (2007). Technetium-99m Pharmaceuticals: Preparation and Quality Control in Nuclear Medicine. New York: Springer. Welch J, Redvanly S. (2003). Handbook of Radiopharmaceuticals – Radiochemistry and Applications. Chichester: John Wiley & Sons.  
  • MetodologiaMethodology
    The teaching methodologies for the theoretical component include exposure of content through slide projection. In the practical component, the contents will be demonstrated in a laboratory context and executed, under guidance, by the student himself. There will also be room for solving problems and issues of a theoretical and practical nature. The UC can be carried out through continuous assessment or final exam. The final classification (CF) of the UC through continuous assessment is obtained from the classifications obtained in the theoretical component (50%) and in the practical component (50%). The theoretical component is evaluated by two written frequencies (50% weighting each). The assessment of the practical component consists of 2 practical tests. The minimum grade for each assessment moment is 8 points. The weighted value of the classifications obtained at each component (teoretical and practical) and at the UC, must be at least 9.5 values.
  • LínguaLanguage
    Português
  • TipoType
    Semestral
  • ECTS
    3
  • NaturezaNature
    Mandatory
  • EstágioInternship
    Não