IPLUSO 19238

Biology and Biochemistry

• ApresentaçãoPresentation

  he Biology component of this course unit deals with the structure and functioning of the cell. Fundamental knowledge on the storage, transmission and use of genetic information in eukaryotic and prokaryotic organisms is transmitted. Cell cycle and gene expression control and related themes such as cancer and apoptosis are also focused. The biochemistry component discusses the concepts of the structure and function of biomolecules and the metabolic pathways in which they are involved. Enzyme functioning and bioenergetics are also focused. Through laboratory practice, the student will perform not only cell biology techniques, but biochemistry techniques such as spectrophotometry that are the basis of various analytical methods. Through practical cases will be developed the ability to analyze, interpret knowledge and facts with application in problem solving.
• ProgramaProgramme

  1. Cellular diversity 2.Organelles and cellular structures; 3. Nucleus, Chromosomes and DNA Replication 4.Geneexpressionmechanism         4.1Transcription 4.2 Translation 5. Cell Division and changes    6. Cell Membrane         6.1 Constitution and Structure          6.2 Transportation    7. Biomolecules    8. Enzymology    9. Introduction to the Biochemistry of Metabolism 10.Metabolism 10.1Glycides 10.2 Lipids and fatty acids      10.3 Proteins 11.Interrelationship of the metabolic pathways     1- Optical microscopy      2-Solutions 3-Potentiometry 4-Isotonicity 5.Spectrophotometry     6- Laboratory evaluation of Glycides
• ObjectivosObjectives

  -Understanding cellular organization and functionality -Know and integrate the functions of organelles -Understand the structure of the membrane and the importance of membrane transport -Understand the role of cell division and its changes in heredity -Know the importance of physiological tampons and interpret their alteration -Study the structure and function of biomolecules (carbohydrates, Proteins and Lipids) -Understand in a global way, the main metabolic pathways and their function -Relate the metabolic and enzymatic changes with the respective pathologies - Promote the ability to analyze, interpret knowledge and facts with application in problem solving
• BibliografiaBibliography

  Alberts, et al - Essential Cell Biology 2nd ed. New York: Garland Publishing. 2004 ISBN 0¿8153¿3481¿8 Alberts, et al.- Molecular Biology of the Cell (5th ed.). New York: Garland Publishing. 2007ISBN-10: 0-8153-4072-9 Stryer L., Gatto G. Tyoczko, J and Berg J.  Biochemistry. 9th ed.. New York: W.H. Freeman Ed. 2019 ISBN-13: 978-1319114671 Halpern e col   - Bioquímica: organização molecular da vida. Lisboa. Lidel Ed   2008. ISBN: 978-972-757-431-5  
• MetodologiaMethodology

  In this curricular unit, the Team-based learning (TBL) methodology is used, with tasks carried out in small groups, allowing the development of the ability to analyze and apply theoretical concepts.
• LínguaLanguage

  Português
• TipoType

  Semestral
• ECTS

  4
• NaturezaNature

  Mandatory
• EstágioInternship

  Não