IPLUSO 19238

Biology and Biochemistry

• ApresentaçãoPresentation

  he Biology component of this course unit deals with the structure and functioning of the cell. Fundamental knowledge on the storage, transmission and use of genetic information in eukaryotic and prokaryotic organisms is transmitted. Cell cycle and gene expression control and related themes such as cancer and apoptosis are also focused. The biochemistry component discusses the concepts of the structure and function of biomolecules and the metabolic pathways in which they are involved. Enzyme functioning and bioenergetics are also focused. Through laboratory practice, the student will perform not only cell biology techniques, but biochemistry techniques such as spectrophotometry that are the basis of various analytical methods. Through practical cases will be developed the ability to analyze, interpret knowledge and facts with application in problem solving.
• ProgramaProgramme

  Cell diversity; Organelles and cellular structures; Nucleus, Chromosomes and DNA Replication Gene expression mechanisms Cell Division and changes Cell Membrane biomolecules enzymology Introduction to the Biochemistry of Metabolism Metabolism Interrelationship of metabolic pathways optical microscopy Solutions potentiometry isotonicity spectrophotometry Laboratory evaluation of carbohydrates
• ObjectivosObjectives

  -Understanding cellular organization and functionality -Know and integrate the functions of organelles -Understand the structure of the membrane and the importance of membrane transport -Understand the role of cell division and its changes in heredity -Know the importance of physiological tampons and interpret their alteration -Study the structure and function of biomolecules (carbohydrates, Proteins and Lipids) -Understand in a global way, the main metabolic pathways and their function -Relate the metabolic and enzymatic changes with the respective pathologies - Promote the ability to analyze, interpret knowledge and facts with application in problem solving
• BibliografiaBibliography

  Alberts, et al - Essential Cell Biology 2nd ed. New York: Garland Publishing. 2004 ISBN 0¿8153¿3481¿8 Alberts, et al.- Molecular Biology of the Cell (5th ed.). New York: Garland Publishing. 2007ISBN-10: 0-8153-4072-9 Stryer L., Gatto G. Tyoczko, J and Berg J. . 9 ed.. New York: W.Biochemistry th H. Freeman Ed. 2019 ISBN-13: 978-1319114671 Halpern e col - Bioquímica: organização molecular da vida . Lisboa. Lidel Ed 2008. ISBN: 978-972-757-431-5  
• MetodologiaMethodology

  In practical classes, the student has prior access to the experimental protocols to be carried out in each class session, which allows for prior reading and preparation. These protocols are accompanied by a set of questions, in order to ensure individual preparation and, subsequently, the discussion of procedures and results.
• LínguaLanguage

  Português
• TipoType

  Semestral
• ECTS

  4
• NaturezaNature

  Mandatory
• EstágioInternship

  Não