IPLUSO 19323

Clinical Biochemistry

• ApresentaçãoPresentation

  Clinical Biochemistry will focus on the relationship between biochemical processes at the cellular level and the physiological processes that occur in mammals (more specifically in the human body), focusing on examples of altered biochemical processes in human diseases. In this sense, the student will have an integrated view of the various metabolic pathways and their regulation, with a greater emphasis on clinical correlations, which describe aberrant biochemical states in disease states (with biochemical and genetic detail), learning that biochemical parameters should be analyzed and monitored. This unit will have an important practical component where the student will use methodologies and analyze parameters used in a clinical laboratory, in order to develop the critical spirit, and the coherent form of presentation of results, which is fundamental in any professional area.
• ProgramaProgramme

  1. Introduction to Clinic Biochemistry 2. Methods used in Clinic Biochemistry. 3. Laboratory evaluation of proteins. 4. Laboratory evaluation of the carbohydrate. 5. Laboratory evaluation of the lipids. 6. Hidoelectolitic balance. 7 Laboratory evaluation of liver function. 8. Laboratory evaluation of renal function 9. Laboratory evaluation of cardic function 10. Serum glucose determination 11. Total cholesterol determination 12. Serum triglycerides determination 13. Serum urea determination 14. Bilirubin determination 15. Alkaline phosphatase determination
• ObjectivosObjectives

  To understand in a global way, the fundamental biochemical mechanisms, their dysfunctions and to understand the application and usefulness of analytical methods. • Understand the structure, function and metabolism of molecules and their biological importance. • Understand the role of biochemistry in the diagnosis and treatment of disease. • Identify the biological product needed to determine each biochemical parameter. • Understand the importance of quality control. • Understand the implications of analytic and non-analytic errors. • Research and critically interpret scientific literature.
• BibliografiaBibliography

  Nader Rifai et al (2019) Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostic 8ª ed, Philadelphia,  W.B.Saunders Company, ISBN: 9781437719406 Kaplan, L.A. et al.(2010) Clinical Chemistry: theory, analysis, correlation, 5th edition, St. Louis, C.V. Mosby Company. ISBN-13: 978-0323036580 McPherson, R and  Pincus, M. (2011) Henry`s (Clinical and Diagnosis Management by Laboratory Methods 22 th edition, W.S. Saunders Company ISBN: 9780323247801 Anderson, S.; Cockane, S. (2003) - Clinical Chemistry Concepts and Applications, McGram- Hill,  ISBN 13:  978-1-57766-514-4
• MetodologiaMethodology

  In practical classes, the student has prior access to the experimental protocols to be carried out in each class session, which allows for prior reading and preparation. These protocols are accompanied by a set of questions, in order to ensure individual preparation and, subsequently, the discussion of procedures and results.  
• LínguaLanguage

  Português
• TipoType

  Semestral
• ECTS

  5
• NaturezaNature

  Mandatory
• EstágioInternship

  Não