IPLUSO 19537
Laboratory Techniques in Hematology
Bioanalysis and Control
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ApresentaçãoPresentationThe curricular unit of Hematology Laboratory techniques is based on an integrated and functional view of the sciences and technologies applied to diagnosis. It aims to endow the students with skills that enable them, within a multidisciplinary team, to contribute to the best quality of care delivery. Its main objectives are to promote the acquisition of new knowledge and laboratory methodologies applied to Hematology and to address the integrated laboratory areas, in a multidisciplinary, cross-sectional and integrative perspective, as a contribution to the correct prognostic and predictive assessment of the disease, as well as the response to therapy.
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ProgramaProgramme1. General notions Hematology Blood (functions, composition) Hematopoiesis Notions of proliferation and apoptosis 2. Hematopoietic organs 3. Hematological parameters used in a laboratory routine 4. Essential factors for erythropoiesis Iron Vitamin B12 Folic acid 5. Haemoglobin Structure of the molecule Heme biosynthesis 6. Physiological erythrocyte hemolysis 7. Morphological changes in the red blood cell Size Shape Content 8. Granulocytopoiesis Kinetics of myeloid cells Functions of granulocytes Cytochemical and immunological markers 9. Mononuclear phagocyte system Monocytopoiesis 10. Lymphocytopoiesis B lymphocytes and humoral response T Lymphocyte and cell response 11. Automatic study of erythrocytes and leukocytes Physiology of Hemostasis Primary Secondary Exploration of the fibrinolytic system Inhibitors and activators
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ObjectivosObjectivesThis curricular unit integrates knowledge covered in Anatomy of disciplines, Histology, Physiology, Biochemistry and Immunology and aims to provide in-depth knowledge of blood tissue, including blood-forming organs and hematopoiesis process as well as morphological, structural and functional aspects of different types of cells blood and its hematopoietic precursors. They will also be developed theoretical concepts and methodologies from the scope of hemostasis. Students must develop skills to obtain blood samples with quality, know the different techniques used in routine hematology laboratory and interpretation with critical spirit cytograms and histograms.
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BibliografiaBibliographySousa, J.C.F., Ferreira, W.C. & Lima, N. (2010). Microbiologia. Edições Lidel. Barroso, H., Meliço-Silveira, A., Taveira, N. (2014). Microbiologia Médica. (Volume 1).Edições Lidel Willey, J., Sherwood, L. & Woolverton, C.J. (2013). Prescott's Microbiology. (9 th ed.). Boston:MacGraw Hill Pádua, M. (2009). Patologia Clínica para Técnicos (Tomo I) Bacteriologia. Lusodidacta. Dacie, J.V. & Lewis, S. M. (2016). Practical Haematology. (12t h ed.). Oxford: Churchill Livingstone.
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MetodologiaMethodologyIn practical classes, the student has prior access to the experimental protocols to be carried out in each class session, which allows for prior reading and preparation. These protocols are accompanied by a set of questions, in order to ensure individual preparation and, subsequently, the discussion of procedures and results.
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LínguaLanguagePortuguês
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TipoTypeSemestral
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ECTS6
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NaturezaNatureMandatory
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EstágioInternshipNão