IPLUSO 19444

Pharmacology and Toxicology Principles

• ApresentaçãoPresentation

  The scope of this CU is to allow the basic principles of Pharmacology and Toxicology to be understood, understanding as the basis of Pharmacology the concept of pharmacon ("drug"), associated with the study of chemicals that interact with biological systems. The UC begins with Drug History through knowledge based on current scientific evidence on drug composition, properties, interactions, toxicology, and desirable effects that can be used in diagnosing, preventing, and treating disease. The CU encompasses knowledge of the history, origin, physical and chemical properties, associations, biochemical and physiological effects, absorption, biotransformation and excretion mechanisms of each drug in each pharmacotherapeutic class according to the ICD-10 International Classification.
• ProgramaProgramme

  Basic concepts in Pharmacology Medicines¿ cycle. Drug information resources Administration routes Pharmacokinetics Pharmacodynamics Therapeutic groups Anti-infectious drugs Musculoskeletal system Cardiovascular pharmacology Drugs acting on blood Nervous system Gastrointestinal system Respiratory pharmacology Vitamins and minerals Rational use of medicines. Essential drugs. Precautions in pregnancy, breastfeeding and pediatrics. Notification of ADRs Principles of Toxicology Dose-response and toxicological parameters Risk assessment. Biomarkers Mutagenesis and Mutagenesis DART Organ-directed toxicology: hepatic, cardiovascular, respiratory, neurologic, renal, locomotor Applied toxicology: solvents, toxins, plants, pesticides, metals Classification of hazardous substances. Material safety data sheets. Regulatory aspects
• ObjectivosObjectives

  The objective of the curricular unit is to provide general knowledge related with drugs that constitutes the basis for the rational use of medicines and allows the consolidation of the practical relevance of the unit for the praxis of a health professional. This curricular unit also aims to introduce the basic concepts of Toxicology, so that these professionals can understand and prevent the risks eventually associated with the treatments that will be applied in their clinical practice. Students should: Demonstrated knowledge on the terminology and basic concepts of Pharmacology Understand the medicines¿ cycle Described the main mechanisms of drug action. Understand the therapeutic uses of the major drug classes, as well as the most representative side effects and interaction Understand the basic principles of Toxicology Understand the potential risks associated with therapeutic interventions
• BibliografiaBibliography

  Goodman, L. S. (2011). Goodman & Gilman¿s. The Pharmacological Basis of Therapeutics. (12th ed.). McGraw Hill. Guimarães, S., Moura, D. & Soares da Silva, P. (2014). Terapêutica Medicamentosa e suas bases Farmacológicas. (6ª ed.). Porto Editora. Infarmed (2013). Prontuário Terapêutico 11. Lu FC, Kacem S. Lu¿s (2012). Basic Toxicology: Fundamentals, Target Organs, and Risk Assessment. (6th ed.). CRC Press.  
• MetodologiaMethodology

  In this curricular unit, the Team-based learning (TBL) methodology is used, with tasks carried out in small groups, allowing the development of the ability to analyze and apply theoretical concepts.
• LínguaLanguage

  Português
• TipoType

  Semestral
• ECTS

  5
• NaturezaNature

  Mandatory
• EstágioInternship

  Não