IPLUSO 18948

Virology

• ApresentaçãoPresentation

  In this curricular unit, viruses will be studied at the level of their molecular and genetic biology, and their interactions with the host organism. Particular emphasis will be placed on viruses that infect humans and cause serious illness. A comparative approach will be adopted, in which a set of questions will be asked from a biophysical and evolutionary perspective.
• ProgramaProgramme

  1. General Features of Viruses 1.1 Introduction to viruses 1.2 Architecture and nomenclature of viruses 1.3 Virus genetics 1.4 Viruscell interaction 1.5 Host resistance to viral infections 1.6 Mechanism of viral replication inhibition 2. Clinical Virology 2.1 Study of pathologies associated with viral infections in humans 2.2 New and emerging viruses 2.3 Epidemiology
• ObjectivosObjectives

  To address the general mechanisms underlying the replication and pathogenesis of viral infections. To study in detail the major causative agents of viral infections in humans and the methods used for its diagnosis. Interconnection of the concepts covered in curricular unit such as cell biology, epidemiology and immunology. Understand the components of the viral particle, the genome organization of the virus and the replication cycle steps. Know the viral and host determinants that influence entry, spread, localisation, virulence and transmission of different viruses. Understand the strategies that allow viruses to evade host defences. Know examples of viral inhibitors and antiviral vaccines. Know the main viruses involved in human diseases. Know the main diagnostic methods (supported by the practical teaching component) and prevention applied to each of these viruses
• BibliografiaBibliography

  Cann, A. J. (2015). Principles of Molecular Virology. (6 ed). Academic Press. th Madigan, M.T. et al., (2014). Brock Biology of Microorganisms. (14 ed.). Upper Saddle River, th PrenticeHall International Editions. Collier, L. Oxford, J. & Kellam, P. (2011). Human Virology. (4 ed.). Oxford University Press. th Nathanson N. (2007). Viral Pathogenesis and Immunity. (2 ed). Academic Press. nd Shors, T. (2016). Understanding Viruses. (3 ed.). Jones & Bartlett Learning (2017).  
• MetodologiaMethodology

  In this curricular unit, the Team-based learning (TBL) methodology is used, with tasks carried out in small groups, allowing the development of the ability to analyze and apply theoretical concepts.
• LínguaLanguage

  Português
• TipoType

  Semestral
• ECTS

  5
• NaturezaNature

  Mandatory
• EstágioInternship

  Não