IPLUSO 19569

Cytopathology II

• ApresentaçãoPresentation

  Cytopathology is crucial for early diagnosis and precision medicine within Anatomic Pathology. The scope of this course focuses on the morphological analysis of non-gynecological exfoliative and fine-needle aspiration cytology (FNAC) samples, aiming to identify malignancy criteria and differential diagnosis. Its domains of intervention encompass pre-analytical validation, the execution of complex protocols (technical processing and Cell-Block preparation), morphological diagnosis within a hybrid screening model (microscopic/digital), and a laboratory approach integrated with the ROSE procedure and EBUS sampling, taught with the support of field specialists. The course relevance within the study cycle lies in training professionals qualified to practice as Cytotechnologists with autonomy and ethics. It empowers them to classify specimens according to International Nomenclatures (Paris, Bethesda and Milan), impacting patient safety.
• ProgramaProgramme

  Cytology: Definition, Objectives, Types of Samples, and Historical Evolution. Cytology as a Diagnostic Tool for Organ Systems. Non-Gynecological and Aspirational Technique: Collection, Reception, Fixation, Technical Processing, and Routine Staining. Cell-Block: Laboratory protocols and technical optimization. Other Complementary Techniques: Immunocytochemistry and Histochemistry. Non-Gynecological Exfoliative Cytology: Serous Cavities (Pleural, pericardial, and peritoneal effusions); Urinary Cytology; Bronchial Cytology: Endobronchial Ultrasound (EBUS) and ROSE (Rapid On-Site Evaluation). Fine Needle Aspiration Cytology (FNAC): Thyroid and Salivary Glands (Brief approach).
• ObjectivosObjectives

  Use advanced technical-scientific terminology in analytical communication within non-gynecological exfoliative and aspirational Cytopathology. Validate the pre-analytical phase and execute technical processing protocols for cytological samples, optimizing Cell-Block preparation. Develop microscopic and digital acuity to distinguish normal cytomorphology from reactive, inflammatory, or infectious changes. Diagnose epithelial or lymphoproliferative neoplasias, integrating morphological criteria into hybrid screening. Classify cytological specimens according to International Nomenclature Systems (Paris, Bethesda and Milan). Understand the operational principles and clinical utility of the ROSE procedure and EBUS sampling. Correlate clinical data through differential reasoning and team-based learning problem-solving. Practice with autonomy and ethics, recognizing the impact of the Cytotechnologist on diagnosis and patient safety.
• BibliografiaBibliography

  Ali, S. Z., & VanderLaan, P. A. (Eds.). (2024). The Bethesda system for reporting thyroid cytopathology (3rd ed.). Springer. https://doi.org/10.1007/978-3-031-28046-7 Chandra, A., Crothers, B., Kurtycz, D., & Schmitt, F. (Eds.). (2020). The international system for serous fluid cytopathology (1st ed.). Springer. https://doi.org/10.1007/978-3-030-53908-5 Faquin, W. C., Rossi, E. D., Baloch, Z., Barkan, G. A., Foschini, M. P., Jain, D., Kurtycz, D. F., & Vielh, P. (Eds.). (2023). The Milan system for reporting salivary gland cytopathology (2nd ed.). Springer. https://doi.org/10.1007/978-3-031-26662-1 Shimbayaty, C., & Shimbova, S. (2024). Cytopathology (2nd ed.). Oxford University Press. https://doi.org/10.1093/med/9780198873210.001.0001 Wojcik, E. M., Kurtycz, D. F., & Rosenthal, D. L. (Eds.). (2024). The Paris system for reporting urinary cytology (2nd ed.). Springer. https://doi.org/10.1007/978-3-030-88687-5
• MetodologiaMethodology

  The course adopts student-centered active methodologies to enhance technical-diagnostic skills. In theoretical and theoretical-practical lectures, Flipped Classroom and digital interactive quizzes are used, promoting continuous formative assessment and immediate conceptual consolidation. The laboratory component is grounded in Team-Based Learning (TBL), where students cooperatively solve clinical mini-sheets based on real cases, developing critical thinking, argumentation skills, and decision-making in differential diagnosis. Methodological innovation is achieved through a hybrid screening model: students train diagnostic acuity by combining high-resolution digital projection with conventional optical microscopy. Additionally, practical classes are conducted with guest specialists, simulating real-world scenarios of Cell-Block processing and advanced procedures (ROSE/EBUS), ensuring an immersive learning experience.  
• LínguaLanguage

  Português
• TipoType

  Semestral
• ECTS

  5
• NaturezaNature

  Mandatory
• EstágioInternship

  Não